Integrative Genetic Element That Reverses the Usual Target Gene Orientation
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TL;DR
A cryptic element in Mesorhizobium loti instead carries a copy of the 5' end of the tRNA gene into which it integrated, which has implications for the evolution of new integrase-site combinations.
Abstract
A genetic element integrating site specifically into a prokaryotic gene usually carries a copy of the 3' portion of that gene that restores the active gene even as the original is disrupted. A cryptic element in Mesorhizobium loti instead carries a copy of the 5' end of the tRNA gene into which it integrated. This has implications for the evolution of new integrase-site combinations.
