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Integrative Genetic Element That Reverses the Usual Target Gene Orientation

Journal of BacteriologyPublished 1 February 2002Open access
Sihui Zhao, Kelly P. Williams
Citations14
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TL;DR

A cryptic element in Mesorhizobium loti instead carries a copy of the 5' end of the tRNA gene into which it integrated, which has implications for the evolution of new integrase-site combinations.

Abstract

A genetic element integrating site specifically into a prokaryotic gene usually carries a copy of the 3' portion of that gene that restores the active gene even as the original is disrupted. A cryptic element in Mesorhizobium loti instead carries a copy of the 5' end of the tRNA gene into which it integrated. This has implications for the evolution of new integrase-site combinations.

Keywords

Agricultural and Biological Sciences