Metabolic Mapping of Functional Activity in the Hypothalamo-Neurohypophysial System of the Rat
SciencePublished 17 August 1979
William J. Schwartz, Carolyn Beebe Smith, Leslie Davidsen, Helen E. Savaki, Louis Sokoloff, Marina Mata
Citations461
SJR quartileQ1
SJR score10.42
SNIP6.62
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TL;DR
A difference in the metabolic response to functional activity between the two regions of these neurons can be explained by the differences in surface-to-volume ratios of these regions.
Abstract
Physiological stimulation of the hypothalamo-neurohypophysial system by salt loading of rats resulted in a dramatically increased glucose utilization in the posterior pituitary but not in the paraventricular or supraoptic nuclei. The good correlation between glucose utilization and neural activity in the posterior pituitary (that is, nerve terminals) contrasted with the lack of correlation in the paraventricular and supraoptic nuclei (that is, the sites of the cell bodies of the same neurons). This difference in the metabolic response to functional activity between the two regions of these neurons can be explained by the differences in surface-to-volume ratios of these regions.
Keywords
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