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Synthesis and cytotoxic properties of a series of bicyclo[3.2.1]octane α-methylene ketones

Tetrahedron LettersPublished 1 April 2001
J. A. MILLER, Ghanim Ullah, G.M Welsh, P. Mallon
Citations12
SJR quartileQ3
SJR score0.33
SNIP0.43

Abstract

Abstract The 8-chlorobicyclo[3.2.1]oct-6-ene 3 has been prepared by a [3+2] cycloaddition route, and converted to the bicyclic α-methylene ketones 6 and 8 – 12 , some of which showed cytotoxic properties.

Keywords

ChemistryBiochemistry, Genetics and Molecular Biology