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Antimicrobial gallic acid from Caesalpinia mimosoides Lamk.

Food ChemistryPublished 28 December 2005
Anchana Chanwitheesuk, Aphiwat Teerawutgulrag, Jeremy Kilburn, Nuansri Rakariyatham
Citations251
SJR quartileQ1
SJR score1.95
SNIP2.15

Abstract

Different extracts of Caesalpinia mimosoides Lamk. (Leguminosae) were tested against eight human pathogenic bacteria and six fungal strains by the disc diffusion method. Among these extracts, the aqueous and the ethanolic extracts showed potent activity against some tested microorganisms. Subsequently, the latter extract was fractionated by means of Sephadex LH-20 column chromatography. A bioactive substance, responsible for the antimicrobial property was separated, and its structure was assigned as a known compound, gallic acid, by extensive chromatographic and spectroscopic analyses.

Keywords

ChemistryImmunology and MicrobiologyMedicine