Risk factors for gall-bladder disease: a cohort study of young women attending family planning clinics
Journal of Epidemiology & Community HealthPublished 1 December 1982Open access
Peter M. Layde, Martin Vessey, David Yeates
Citations112
SJR quartileQ1
SJR score1.78
SNIP1.24
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TL;DR
During 1968-74, 17 032 women aged 25-39 years were recruited to the Oxford/Family Planning Association Contraceptive Study, and 227 of these women had suffered surgically confirmed gall-bladder disease during the follow-up period, an incidence of 1·47 per 1000 woman-years.
Abstract
During 1968-74, 17 032 women aged 25-39 years were recruited to the Oxford/Family Planning Association Contraceptive Study. By the end of August 1981, 227 of these women had suffered surgically confirmed gall-bladder disease during the follow-up period, an incidence of 1·47 per 1000 woman-years. Obesity was by far the strongest risk factor for gall-bladder disease, but late age at first term birth and cigarette smoking also had statistically significant independent effects. The influence of the use of oral contraceptives on risk was small.
Keywords
Medicine
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