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Sexual dimorphism in circulating leptin concentrations is not accounted for by differences in adipose tissue distribution

International Journal of ObesityPublished 1 September 2001
Michael Rosenbaum, Angelo Pietrobelli, JR Vasselli, S. B. Heymsfield, RL Leibel
Citations94
SJR quartileQ1
SJR score1.59
SNIP1.33

TL;DR

The sexual dimorphism in plasma leptin concentration appears to reflect, at least in part, effects of circulating concentrations of gonadal steroids (especially androgens) and/or primary genetic differences that are independent of amounts of VAT or SAT.

Abstract

The sexual dimorphism in the relationship between leptin and adipose tissue mass cannot be explained by differences in the relative amounts of VAT and SAT. Thus, the sexual dimorphism in plasma leptin concentration appears to reflect, at least in part, effects of circulating concentrations of gonadal steroids (especially androgens) and/or primary genetic differences that are independent of amounts of VAT or SAT.

Keywords

MedicineNeuroscience