Functional Magnetic Resonance Imaging of Motor Cortex: Hemispheric Asymmetry and Handedness
SciencePublished 30 July 1993
Seong‐Gi Kim, James Ashe, Kristy Hendrich, Jutta Ellermann, Hellmut Merkle, Kǎmil Uǧurbil
Citations994
SJR quartileQ1
SJR score10.42
SNIP6.62
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
A hemispheric asymmetry in the functional activation of the human motor cortex during contralateral (C) and ipsilateral (I) finger movements, especially in right-handed subjects, was documented with nuclear magnetic resonance imaging at high field strength.
Abstract
A hemispheric asymmetry in the functional activation of the human motor cortex during contralateral (C) and ipsilateral (I) finger movements, especially in right-handed subjects, was documented with nuclear magnetic resonance imaging at high field strength (4 tesla). Whereas the right motor cortex was activated mostly during contralateral finger movements in both right-handed (C/I mean area of activation = 36.8) and left-handed (C/I = 29.9) subjects, the left motor cortex was activated substantially during ipsilateral movements in left-handed subjects (C/I = 5.4) and even more so in right-handed subjects (C/I = 1.3).
Keywords
MedicineNeuroscience
NeuropsychologiaThe assessment and analysis of handedness: The Edinburgh inventory
36,704 Citations1971R. C. Oldfield
An inventory of 20 items with a set of instructions and response- and computational-conventions is proposed and the results obtained from a young adult population numbering some 1100 individuals are reported.
BrainDISCONNEXION SYNDROMES IN ANIMALS AND MAN
3,402 Citations1965Norman Geschwind
This paper would never have been written without Professor Zangwill’s urging, and I am grateful to him for having brought me to a more careful review of the older literature and a more precise statement of my own ideas.
Journal of Magnetic ResonanceFLASH imaging: Rapid NMR imaging using low flip-angle pulses
1,165 Citations2011Axel Haase, Jens Frahm +3 more
A new method for rapid NMR imaging dubbed FLASH ( fast low-a ngle sh ot) imaging is described which allows measuring times of the order of 1 s (64 × 128 pixel resolution) or 6 s (256 × 256 pixels), resulting in about a 100-fold reduction in measuring time without sacrificing spatial resolution.
Annals of NeurologyThe functional anatomy of motor recovery after stroke in humans: A study with positron emission tomography
1,097 Citations1991François Chollet, Vittorio Di Piero +4 more
The results suggest that ipsilateral motor pathways may play a role in the recovery of motor function after ischemic stroke.
Left brain, right brain
859 Citations1950Sally P. Springer, G.P. Deutsch
Journal of NeurophysiologyRegional cerebral blood flow during voluntary arm and hand movements in human subjects
600 Citations1991James G. Colebatch, Marie‐Pierre Deiber +3 more
The data indicate that neither "fractionation" nor distal movement per se cause selective activation of sensorimotor cortex, and this finding does not prove unequivocally a "selective" role of the nonprimary motor areas in proximal movement.
BrainACQUISITION OF A MOTOR SKILL AFTER LEFT-HEMISPHERE DAMAGE
423 Citations1977Doreen Kimura
It was concluded that a major function of the left hemisphere is the control of changes in limb or articulatory posture, and that its complex verbal and praxic functions are derived from such control.
Journal of NeurophysiologyFunctional imaging of human motor cortex at high magnetic field
376 Citations1993Seung‐Goo Kim, James Ashe +6 more
This work used conventional gradient echo magnetic resonance imaging at high field strength (4 Tesla) to functionally image the right motor cortex in six normal human subjects during the performance of a sequence of self-paced thumb to digit oppositions with the left hand, the right hand, and both hands.
NeuropsychologiaHemispheric control of the initial and corrective components of aiming movements
181 Citations1989Kathleen Y. Haaland, Deborah L. Harrington
Regardless of the movement amplitude the left hemisphere group's reaction time was slower, and the execution of the initial movement component was less accurate than controls, but performance was not impaired for the right hemisphere group on any measures.
NeuropsychologiaMotor deficits after left or right hemisphere damage due to stroke or tumor
168 Citations1981Kathleen Y. Haaland, Harold D. Delaney
The hypothesis that the tasks which require greater sensory-motor interaction require more neural control and are more likely to be disrupted after brain damage, regardless of lateralization is best explained.
NeuropsychologiaThe effect of brain lesions in the performance of an arm-hand precision task
90 Citations1968Maria Wyke
The results show that left- and right-sided cerebral lesions produce significant alterations in the ability to perform precise movements, in both the ipsilateral as well as the contralateral arm to the lesion.
NeurologyRegional cerebral blood flow comparison of right and left hand movement
83 Citations1979James H. Halsey, Urs W. Blauenstein +2 more
Regional cerebral blood flow measurements were made in normal right-handed subjects by the 133 xenon inhalation method at rest and during movement of either hand, suggesting that more effort is required of right- handed subjects to move the left hand than the right, or that motor organization differs for left and right hand movements.
NeuropsychologiaThe effects of task complexity on motor performance in left and right CVA patients
70 Citations1987Kathleen Y. Haaland, Deborah L. Harrington +1 more
Quantified CT scan analyses indicated lesion volume was similar between CVA groups, but the left hemisphere group's lesions were more anterior, and the results are discussed in terms of inter- and intrahemispheric roles in open and closed loop movements.
Archives of NeurologyPostural Arm Drift Associated With Brain Lesions in Man
43 Citations1966Maria Wyke
It is seldom appreciated that very few experimental studies have been made of the extent of postural arm drift in normal subjects; nor has any attempt been made to establish whether a subject's ability to maintain static postures is better with one arm than with the other.