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Oral Clonidine in Postmenopausal Patients with Breast Cancer Experiencing Tamoxifen-Induced Hot Flashes: A University of Rochester Cancer Center Community Clinical Oncology Program Study

Annals of Internal MedicinePublished 16 May 2000
Kishan J. Pandya, Richard F. Raubertas, Patrick J. Flynn, Harry E. Hynes, Richard J. Rosenbluth, Jeffrey J. Kirshner
Citations309
SJR quartileQ1
SJR score3.38
SNIP3.27

TL;DR

A larger randomized, controlled trial was performed that studied the effect of clonidine on hot flashes in women receiving tamoxifen for breast cancer and found its effectiveness in controlling hot flashes caused by natural or surgical menopause.

Abstract

Oral clonidine, 0.1 mg/d, is effective against tamoxifen-induced hot flashes in postmenopausal women with breast cancer.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology