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Important Issues in the Drug Treatment of Schizophrenia

Schizophrenia BulletinPublished 1 January 1980
John M. Davis, C. B. Schaffer, G. A. Killian, Carl O. Kinard, Chetwyn C. H. Chan
Citations284
SJR quartileQ1
SJR score2.14
SNIP1.67

TL;DR

The large body of research demonstrating the effectiveness of antipsychotic drugs in the treatment of acute schizophrenia is selectively reviewed and recommendations are made concerning areas of psychopharmacologic research that require further development.

Abstract

The large body of research demonstrating the effectiveness of antipsychotic drugs in the treatment of acute schizophrenia is selectively reviewed. Research evidence relevant to the following issues is assessed; indications for selective treatment; characteristics of drug responders and nonresponders; indications for high dosage phenothiazine treatment; indications for maintenance therapy; benefits and risks of antipsychotic drugs. Recommendations are made concerning areas of psychopharmacologic research that require further development.

Keywords

MedicineNeuroscience