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Memory trace reactivation in hippocampal and neocortical neuronal ensembles

Current Opinion in NeurobiologyPublished 1 April 2000
Gary R. Sutherland
Citations381
SJR quartileQ1
SJR score2.54
SNIP1.27

TL;DR

Investigations have shown that during 'off-line' periods, traces of these experiences are spontaneously reactivated in hippocampal and neocortical neuronal activity, providing clues about the nature and mechanisms of memory retrieval and consolidation.

Abstract

During active behavior, patterns of hippocampal and neocortical neuronal activity reflect ongoing inputs and their contexts. Recent neurophysiological investigations have shown that during 'off-line' periods, traces of these experiences are spontaneously reactivated in both structures. Although the functional importance of this phenomenon remains to be demonstrated, it does provide clues about the nature and mechanisms of memory retrieval and consolidation.

Keywords

Neuroscience