Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolemia (ASAP): a prospective, randomised, double-blind trial
The LancetPublished 1 February 2001
TJ Smilde, Sanne van Wissen, H Awollersheim, M van Linde-Sibenius Trip, Jjp Kastelein, A.F.H. Stalenhoef
Citations920
SJR quartileQ1
SJR score12.11
SNIP22.72
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TL;DR
The results show that aggressive LDL-cholesterol reduction by atorvastatin was accompanied by regression of carotid intima media thickness in patients with familial hypercholesterolaemia, whereas conventional LDL lowering was not.
Abstract
Our results show that aggressive LDL-cholesterol reduction by atorvastatin was accompanied by regression of carotid intima media thickness in patients with familial hypercholesterolaemia, whereas conventional LDL lowering was not.
Keywords
Immunology and MicrobiologyMedicine
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