The Role of Macrophages in Atherosclerosis
Hämatologie und BluttransfusionPublished 1 January 1981
Hans‐Eckart Schaefer
Citations39
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TL;DR
The development of arteriosclerosis results from diverse pathogenetic sources, and it is conceivable that the course of morphogenesis as well as the ultimate picture of arte- riosclerosic lesions appears more or less heterogeneous.
Abstract
The development of arteriosclerosis results from diverse pathogenetic sources, and it is conceivable, therefore, that the course of morphogenesis as well as the ultimate picture of arte- riosclerosic lesions appears more or less heterogeneous [8]. Nevertheless, the formation of atheroma (fibrofatty plaque, gruel plaque) represents a hallmark of what is called in a strict sense atherosclerosis. Most atherosclerosis-linked symptoms of clinical relevance can be considered as direct sequelae of fibrofatty plaques. For instance, an atheroma can induce coronary heart disease by its occlusive action, and secondary ulcerative lesions lead to thromboembolic complications.
Keywords
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