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The Dexamethasone Suppression Test in Psychotic versus Non-psychotic Endogenous Depression

The British Journal of PsychiatryPublished 1 November 1984
Zoltán Rihmer, Mihály Arató, Erika Szádóczky, Katalin Révai, E. Demeter, S. György
Citations32
SJR quartileQ1
SJR score2.47
SNIP2.17

TL;DR

The authors investigated the dexamethasone suppression test in 93 female patients with primary (endogenous) major depression; in 20 female paranoid schizophrenics, and in 17 healthy females, where the unipolar and bipolar depressives showed a similar profile of DST abnormalities.

Abstract

The authors investigated the dexamethasone suppression test (DST) in 93 female patients with primary (endogenous) major depression; in 20 female paranoid schizophrenics, and in 17 healthy females. Depressed patients had a significantly higher rate of abnormal DST response and significantly higher post-dexamethasone serum cortisol levels than schizophrenics and normal controls. The unipolar and bipolar depressives showed a similar profile of DST abnormalities. Depressed patients with psychotic features had a significantly higher rate of positive DST results than non-psychotic patients.

Keywords

MedicineNeuroscience