fi− R Factors giving Chloramphenicol Resistance
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TL;DR
In this study, R factors from the fish pathogen Aeromonas liquefaciens were described, which were all fi− and some of which carried chloramphenicol resistance determinants.
Abstract
ALTHOUGH many fi+ R factors confer resistance to chloramphenicol, fi− R factors seldom do. Watanabe et al.1 stated in 1964 that all the naturally occurring fi− R factors which they had studied lacked chloramphenicol resistance. In our laboratory, no fi− R factor giving chloramphenicol resistance has been observed among several hundred drug-resistant strains of enteric bacteria. In 1968 Watanabe, Furuse and Sakaizumi2 reported an fi− R factor (S–a) from Shigella which conferred chloramphenicol resistance at about the same level as fi+ R factors. Aoki, Egusa, Ogata and Watanabe3 this year described R factors from the fish pathogen Aeromonas liquefaciens, which were all fi− and some of which carried chloramphenicol resistance determinants.