Antipsychotic Use Among Nursing Home Residents
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TL;DR
The concerns about enrolling patients with prevalent -blocker use and immortal time bias are valid and are limitations of the study, but it should be noted that the results of this observational study are not vastly different from those of RCTs.
Abstract
The prescribing of antipsychotic medications persists at high levels in US nursing homes (NHs) despite extensive data demonstrating marginal clinical benefits and serious adverse effects, including death.1- 2 However, imprecise and outdated data have limited the understanding of the current state of antipsychotic medication prescribing in NHs.3 We analyzed recent and detailed NH prescription data to address: (1) What is the current level of antipsychotic use? (2) Does antipsychotic use in NHs display geographic variation? and (3) Which antipsychotics are most commonly prescribed?