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Impact of selective antimicrobial agents on staphylococcal adherence to biomedical devices

The American Journal of SurgeryPublished 22 August 2006
Charles E. Edmiston, Michael P. Goheen, Gary R. Seabrook, Christopher P. Johnson, Brian D. Lewis, Kellie R. Brown
Citations87
SJR quartileQ1
SJR score0.95
SNIP1.17

TL;DR

Daptomycin, rifampin, and linezolid demonstrated greater efficacy and speed in eradicating microbial adherence of staphylococcal isolates from selected devices compared with vancomycin, gentamicin, or ceftriaxone (P<.01).

Abstract

Daptomycin, rifampin, and linezolid demonstrated greater efficacy and speed in eradicating microbial adherence of staphylococcal isolates from selected devices compared with vancomycin, gentamicin, or ceftriaxone (P<.01). Further studies are warranted, however, to validate the clinical efficacy of daptomycin and linezolid in the treatment of biomedical device-associated infections.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology