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Estrogen Replacement Therapy and Risk of Fatal Colon Cancer in a Prospective Cohort of Postmenopausal Women

JNCI Journal of the National Cancer InstitutePublished 5 April 1995
E. E. Calle, Heidi L. Miracle-McMahill, Michael J. Thun, C. W. Heath
Citations361
SJR quartileQ1
SJR score5.70
SNIP2.66

TL;DR

In the data, estrogen therapy, particularly recent and long-term use, was associated with a substantial decrease in risk of fatal colon cancer, consistent with several published studies suggesting a protective role of exogenous estrogens in the development of colorectal cancer.

Abstract

In our data, estrogen therapy, particularly recent and long-term use, was associated with a substantial decrease in risk of fatal colon cancer. These results were consistent with several published studies suggesting a protective role of exogenous estrogens in the development of colorectal cancer and merit further investigation.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology