Reduction in the antibacterial effect of oxy-tetracycline in sea water by complex formation with magnesium and calcium
Diseases of Aquatic OrganismsPublished 1 January 1990Open access
BT Lunestad, Jostein Goksøyr
Citations180
SJR quartileQ3
SJR score0.36
SNIP0.55
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TL;DR
The con~plex constants are determined and it is calculated that when therapeutic concentrations of OT are present in sea water, only about 5 O/O of the OT exists in the free form, which results in a strong reduction in the antibacterial effect of OT.
Abstract
Oxytetracycline (OT) is used extensively in the treatment of bacterial diseases in marine f ~s h .
Keywords
Pharmacology, Toxicology and PharmaceuticsEnvironmental Science
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