Urinary Coproporphyrins in Lead Poisoning
Occupational and Environmental MedicinePublished 1 April 1952Open access
J. E. Kench, R. E. Lane, H. Varley
Citations16
SJR quartileQ1
SJR score1.34
SNIP1.27
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TL;DR
Rimington (1936) advanced the view that in enzymic synthesis of the porphyrins, a small amount of type I series is always produced, which, being of no value, is excreted, and urinary coproporphyrin I excretion provided an index of the rate of haemopoiesis.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
BloodPhotosensitive or Congenital Porphyria with Hemolytic Anemia
71 Citations1951Robert A. Aldrich, Violet Hawkinson +2 more
The striking decline in formation of copro- and uroporphyrin after splenectomy is believed to be correlated directly with the reduced erythropoiesis incident to removal of the excessive hemolysis and is more consistent with the view that copropoiryrin I is a precursor of uro- I, or that both porphyrins are synthesized independently from common precursors.
Occupational and Environmental MedicineCare Of The Lead Worker
50 Citations1949R. E. Lane
The history of industrial lead poisoning in this country over the last eighty years provides an excellent example of preventive medicine, and the use of lead is still increasing, and if this is to remain safe the informed help of medical men will be required.
Journal of Clinical InvestigationCONCERNING THE NATURALLY OCCURRING PORPHYRINS. IV. THE URINARY PORPHYRIN IN LEAD POISONING AS CONTRASTED WITH THAT EXCRETED NORMALLY AND IN OTHER DISEASES 1
46 Citations1936C. J. Watson
QJMON THE NATURE AND SIGNIFICANCE OF STIPPLING IN LEAD POISONING, WITH REFERENCE TO THE EFFECT OF SPLENECTOMY
41 Citations1949A. J. S. McFadzean, L. J. Davis
Biochemical JournalA simple fluorescence comparator and its application to the determination of porphyrin
24 Citations1943C. Rimington
Journal of Clinical InvestigationTHE EXCRETION OF COPROPORPHYRIN I FOLLOWING HEMORRHAGE IN DOGS
22 Citations1938Konrad Dobriner, C. P. Rhoads
The simple experiment has been made of measuring quantitatively the rate of excretion of coproporphyrin I in normal dogs during control periods and then during periods of increased hematopoietic activity following anemia due to the removal of blood, to avoid any possibility of the resynthesis of the products of the breakdown of Type III porphyrins to those of Type I structure.
Biochemical JournalThe determination of minute amounts of lead in urine
13 Citations1940J. E. Kench
Tompsett's method, the writer experienced losses during the recovery of lead from urine owing to its entrainment with phosphate and finely divided silica, but Digestion with deleaded H2S04 to destroy organic material and the use of perhydrol overcame these difficulties.