Efficacy and Safety of Oral Conivaptan: A V<sub>1A</sub>/V<sub>2</sub>Vasopressin Receptor Antagonist, Assessed in a Randomized, Placebo-Controlled Trial in Patients with Euvolemic or Hypervolemic Hyponatremia
The Journal of Clinical Endocrinology & MetabolismPublished 8 March 2006Open access
Jalal K. Ghali, Michael J. Koren, James R. Taylor, Esther M. Brooks-Asplund, Kaisheng Fan, Walker Long
Citations192
SJR quartileQ1
SJR score2.18
SNIP1.77
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TL;DR
Oral conivaptan (40 and 80 mg/d) was well tolerated and efficacious in correcting serum [Na(+)] in hyponatremia, and headache, hypotension, nausea, constipation, and postural hypotension were the most common adverse events.
Abstract
Oral conivaptan (40 and 80 mg/d) was well tolerated and efficacious in correcting serum [Na(+)] in hyponatremia.
Keywords
MedicineNeuroscience
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