Effects of lorazepam and scopolamine on encoding face-name associations: A pharmacologic fMRI trial

This work sought to test the hypothesis that pharmacologically induced memory impairments are associated with anatomically specific alterations in patterns of fMR1 activation, using a face-name paired associated learning paradigm.

Abstract

Introduction: Recent functional neuroimaging studies have reported robust activation in the hippocampus and related structures with memory paradigms, and a small number of studies have reported reduced activation in these regions in patients with memory impairment. We sought to test the hypothesis that pharmacologically induced memory impairments are associated with anatomically specific alterations in patterns of fMR1 activation, using a face-name paired associated learning paradigm.