Optimal Therapeutic Range for Oral Anticoagulants
CHEST JournalPublished 1 February 1989
Jack Hirsh, L. Poller, Daniel Deykin, Mark N. Levine, James E. Dalen
Citations153
SJR quartileQ1
SJR score1.83
SNIP1.83
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Abstract
The optimal therapeutic range for oral anticoagulant therapy was reviewed by the Committee on Antithrombotic Therapy of the American College of Chest Physicians (ACCP) and the National Heart, Lung and Blood Institute (NHLBI) at their first conference. Their recommendation that the intensity of warfarin treatment should be reduced for many conditions1,2 was based on the results of randomized clinical trials.
Keywords
Medicine
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35 Citations1990Alexander G.G. Turpie
The study used the development of left ventricular mural thrombosis, a frequent complication of acute myocardial infarction that carries a high risk for systemic embolic complications, to assess clinical outcome and suggests that monitoring plasma heparin levels and anticoagulant response can ensure maximal treatment effectiveness.
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28 Citations1988L. Poller
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28 Citations1957Marc Verstraete, Patricia A. Clark +1 more
An evaluation of the dependability and significance of different types of tissue thromboplastin in the determination of effects of coumarin derivatives is presented.
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27 Citations1981Z Latałło, J M Thomson +1 more
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Journal of Clinical PathologySurvey of prothrombin time in National External Quality Assessment Scheme exercises (1980-87).
25 Citations1988L. Poller, D A Taberner +2 more
Performance of the other Quick test reagents had not regained the standards of precision previously achieved by the human brain reagent, and only one reagent (ISI 1.1) showed an improvement in precision when the recent results from 1986-87 were analysed.
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19 Citations1986G.O. Gogstad, J Wadt +2 more
This is the first study in which three independent laboratories demonstrate a similar bias of the WHO calibration model and a modified model in which a correction factor is introduced was applied and proved to give a reliable calculation method for INR on Normotest.