Vasopressin Analogs That Antagonize Antidiuretic Responses by Rats to the Antidiuretic Hormone
SciencePublished 3 April 1981
W. H. Sawyer, P.K.T. Pang, J. SETO, Maryann McEnroe, B. Lammek, M. Manning
Citations116
SJR quartileQ1
SJR score10.42
SNIP6.62
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TL;DR
Four new synthetic analogs of vasopressin (antidiuretic hormone) can antagonize the antidiureic response to intravenous vasopressed rats in anesthetized, water-loaded rats.
Abstract
Four new synthetic analogs of vasopressin (antidiuretic hormone) can antagonize the antidiuretic response to intravenous vasopressin in anesthetized, water-loaded rats. They also cause a diuresis resembling that of diabetes insipidus when given intraperitoneally to conscious rats. Such antagonists may prove to be useful both pharmacologically and therapeutically.
Keywords
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