Lack of effect of tricyclic antidepressants on serum prolactin levels
PsychopharmacologyPublished 1 January 1977
Herbert Y. Meltzer, Songkait Piyakalmala, Paul M. Schyve, Victor S. Fang
Citations57
SJR quartileQ1
SJR score1.16
SNIP0.97
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TL;DR
The results indicate that blockade of serotonin reuptake does not affect basal prolactin levels in man and no increases after acute or chronic treatment with either drug in usual clinical doses.
Abstract
A previous report indicated that the tricyclic antidepressants imipramine and amitriptyline markedly increased plasma prolactin levels in man. We found no increases after acute or chronic treatment with either drug in usual clinical doses. The results indicate that blockade of serotonin reuptake does not affect basal prolactin levels in man.
Keywords
Medicine
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