A phage repressor–operator complex at 7 Å resolution
NaturePublished 1 August 1985
John E. Anderson, Mark Ptashne, Stephen C. Harrison
Citations138
SJR quartileQ1
SJR score18.29
SNIP10.16
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TL;DR
The crystal structure of a complex between the DNA-binding domain of phage 434 repressor and a synthetic 434 operator shows that the protein binds to B-form DNA with the second α-helix of a helix–turn–helix motif lying in the major groove.
Abstract
The crystal structure of a complex between the DNA-binding domain of phage 434 repressor and a synthetic 434 operator shows that the protein, very similar in conformation to gamma repressor, binds to B-form DNA with the second alpha-helix of a helix-turn-helix motif lying in the major groove.
Keywords
Biochemistry, Genetics and Molecular BiologyEnvironmental Science
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