Asymmetric intermolecular Stetter reactions catalyzed by a novel triazolium derived N-heterocyclic carbene
Chemical CommunicationsPublished 1 January 2008
Dieter Enders, Jianwei Han, Alexander Henseler
Citations194
SJR quartileQ1
SJR score1.04
SNIP0.78
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TL;DR
The asymmetric intermolecular Stetter reaction is catalyzed by a novel triazolium salt derived N-heterocyclic carbene leading to 1,4-diketones in moderate to excellent yields and moderate to good enantioselectivities, which could be enhanced by one recrystallization to excellent levels.
Abstract
The asymmetric intermolecular Stetter reaction is catalyzed by a novel triazolium salt derived N-heterocyclic carbene leading to 1,4-diketones in moderate to excellent yields (49-98%) and moderate to good enantioselectivities (56-78% ee), which could be enhanced by one recrystallization to excellent levels (90-99% ee).
Keywords
Chemistry
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