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Sensitivity of the Multispot HIV-1/HIV-2 Rapid Test Using Samples from Human Immunodeficiency Virus Type 1-Positive Individuals with Various Levels of Exposure to Highly Active Antiretroviral Therapy

Journal of Clinical MicrobiologyPublished 1 May 2006Open access
Robert J. O’Connell, Brian K. Agan, Stephanie A. Anderson, Jennifer Malia, Nelson L. Michael
Citations22
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TL;DR

The Multispot HIV-1/H HIV-2 rapid test detects human immunodeficiency virus type 1 (HIV-1) gp41 antibodies, which can wane over time in some HIV- 1-infected populations, resulting in false-negative screening results.

Abstract

The Multispot HIV-1/HIV-2 rapid test detects human immunodeficiency virus type 1 (HIV-1) gp41 antibodies, which can wane over time in some HIV-1-infected populations, resulting in false-negative screening results. Multispot sensitivity was 100% using 248 sera from one such population, and it correctly identified serostatus in individuals who previously tested false negative with rapid testing.

Keywords

Immunology and MicrobiologyMedicine