Medroxyprogesterone acetate antiandrogen treatment of hypersexuality in a pedophiliac sex offender
American Journal of PsychiatryPublished 1 August 1983
Oscar A. Cordoba, James L. Chapel
Citations39
SJR quartileQ1
SJR score5.27
SNIP3.68
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TL;DR
Medroxyprogesterone therapy resulted in decreased libido, few side effects, and no recurrence of sex offenses, but there was no change in the patient's sexual orientation.
Abstract
A hypersexual pedophiliac sex offender was treated with the antiandrogen medroxyprogesterone acetate for 500 days. During the treatment, his testosterone blood levels significantly decreased, nearly to female values. Pituitary gonadotropin and urinary steroid metabolite levels diminished initially. Medroxyprogesterone therapy resulted in decreased libido, few side effects, and no recurrence of sex offenses, but there was no change in the patient's sexual orientation.
Keywords
PsychologyMedicine
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72 Citations1974T. S. Davies
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35 Citations1978Pinta Er
A male patient with obsessive homosexual pedophilic fantasies treated with psychotherapy and medroxyprogesterone acetate, a progestin with antiandrogen activity was administered and MPA was observed to have psychological benefits that outlived its physiologic activity.
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