Zn-Proline catalyzed direct aldol reaction in aqueous mediaElectronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b3/b301117h/
Chemical CommunicationsPublished 31 March 2003
Tamis Darbre, Miguel Machuqueiro
Citations187
SJR quartileQ1
SJR score1.04
SNIP0.78
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TL;DR
Zn complexes of proline, lysine and arginine are efficient catalysts for the aldol addition of p-nitrobenzaldehyde and acetone in aqueous medium, giving quantitative yields and enantiomeric excesses up to 56% with 5 mol% of the catalysts at room temperature.
Abstract
Zn complexes of proline, lysine and arginine are efficient catalysts for the aldol addition of p-nitrobenzaldehyde and acetone in aqueous medium, giving quantitative yields and enantiomeric excesses up to 56% with 5 mol% of the catalysts at room temperature.
Keywords
ChemistryBiochemistry, Genetics and Molecular Biology
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