Exercise Plus Behavioral Management in Patients With Alzheimer Disease
JAMAPublished 14 October 2003Open access
Linda Teri, Laura E. Gibbons, Susan M. McCurry, Rebecca G. Logsdon, David M. Büchner, William E. Barlow
Citations759
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TL;DR
Exercise training combined with teaching caregivers behavioral management techniques improved physical health and depression in patients with Alzheimer disease.
Abstract
Exercise training combined with teaching caregivers behavioral management techniques improved physical health and depression in patients with Alzheimer disease.
Keywords
Medicine
Journal of Psychiatric Research“Mini-mental state”
86,858 Citations1975Marshal F. Folstein, Susan E. Folstein +1 more
A simplified, scored form of the cognitive mental status examination, the “Mini-Mental State” (MMS) which includes eleven questions, requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
Journal of Neurology Neurosurgery & PsychiatryA RATING SCALE FOR DEPRESSION
32,633 Citations1960M. Hamilton
The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
NeurologyClinical diagnosis of Alzheimer's disease
27,993 Citations1984Guy M. McKhann, David A. Drachman +4 more
The criteria proposed are intended to serve as a guide for the diagnosis of probable, possible, and definite Alzheimer's disease; these criteria will be revised as more definitive information becomes available.
BiometrikaLongitudinal data analysis using generalized linear models
18,123 Citations1986Kung‐Yee Liang, Scott L. Zeger
Journal of GerontologyA Short Physical Performance Battery Assessing Lower Extremity Function: Association With Self-Reported Disability and Prediction of Mortality and Nursing Home Admission
9,728 Citations1994Jack M. Guralnik, E. M. Simonsick +6 more
Evidence is presented that performance measures can validly characterize older persons across a broad spectrum of lower extremity function and that performance and self-report measures may complement each other in providing useful information about functional status.
British Journal of Social and Clinical PsychologyDevelopment of a Rating Scale for Primary Depressive Illness
8,470 Citations1967Max Hamilton
This is an account of further work on a rating scale for depressive states, including a detailed discussion on the general problems of comparing successive samples from a ‘population’, the meaning of factor scores, and the other results obtained.
Journal of GerontologyFunctional Reach: A New Clinical Measure of Balance
2,878 Citations1990Pamela W. Duncan, D. Weiner +2 more
FR is portable, inexpensive, reliable, precise, and a reasonable clinical approximator of the margin of stability, and may be useful for detecting balance impairment, change in balance performance over time, and the design of modified environments for impaired older persons.
Biological PsychiatryCornell scale for depression in dementia
2,634 Citations1988George S. Alexopoulos, Robert C. Abrams +2 more
Archives of Internal MedicineEffects of Exercise Training on Older Patients With Major Depression
1,263 Citations1999James A. Blumenthal, Michael A. Babyak +10 more
After 16 weeks of treatment exercise was equally effective in reducing depression among patients with MDD, and an exercise training program may be considered an alternative to antidepressants for treatment of depression in older persons.
Psychology and AgingAssessment of behavioral problems in dementia: The Revised Memory and Behavior Problems Checklist.
1,004 Citations1992Linda Teri, Paula Truax +3 more
JAMADiagnosis and Treatment of Alzheimer Disease and Related Disorders
932 Citations1997Gary W. Small
A consensus conference on the diagnosis and treatment of Alzheimer disease and related disorders was organized by the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society on January 4 and 5, 1997, and reached consensus.
Journal of the American Geriatrics SocietyRisk Factors for Serious Injury During Falls by Older Persons in the Community
916 Citations1995Mary E. Tinetti, John T. Doucette +2 more
The frequency of, and risk factors for, experiencing serious fall injury events among older persons in the community are determined.
Journal of GerontologyPredictors of Functional Recovery One Year Following Hospital Discharge for Hip Fracture: A Prospective Study
824 Citations1990Jay Magaziner, Eleanor M. Simonsick +3 more
It is found that those who are older, have longer hospital stays, and are rehospitalized, exhibit poorer recovery, as do those displaying chronic or acute cognitive deficits and depressive symptomatology while hospitalized.
JAMAA Family Intervention to Delay Nursing Home Placement of Patients With Alzheimer Disease
817 Citations1996Mary Mittelman
A program of counseling and support can substantially increase the time spouse-caregivers are able to care for AD patients at home, particularly during the early to middle stages of dementia when nursing home placement is generally least appropriate.
The Journals of Gerontology Series BBehavioral Treatment of Depression in Dementia Patients: A Controlled Clinical Trial
653 Citations1997Linda Teri, R. G. Logsdon +2 more
Results indicate that behavioral interventions for depression are important and effective strategies for treating demented patients and their caregivers.
Arthritis & RheumatismComparative measurement efficiency and sensitivity of five health status instruments for arthritis research
601 Citations1985Matthew H. Liang, Martin G. Larson +2 more
Five health status instruments were administered in random order to 50 arthritis patients before and after total joint arthroplasty, and no single instrument consistently outperformed the others.
JAMAFalls and Fractures in Patients With Alzheimer-Type Dementia
478 Citations1987David M. Büchner
Patients who experienced toxic reactions to drugs on entry into the study were more likely to report they had fallen prior to entry, and patients who wandered were more than three times the age- and sex-adjusted fracture rate in the general population.
The British Journal of PsychiatryEffects of exercise on depressive symptoms in older adults with poorly responsive depressive disorder
369 Citations2002Anne S. Mather, César A. Rodríguez +4 more
Because exercise was associated with a modest improvement in depressive symptoms at 10 weeks, older people with poorly responsive depressive disorder should be encouraged to attend group exercise activities.
The Journals of Gerontology Series AThe Efficacy of Exercise as a Long-term Antidepressant in Elderly Subjects: A Randomized, Controlled Trial
350 Citations2001Nihal Singh, Karen M. Clements +1 more
Unsupervised weight-lifting exercise maintains its antidepressant effectiveness at 20 weeks in depressed elderly patients, suggesting long-term changes in exercise behavior are possible in some patients even without supervision.
Journal of GerontologySenile Dementia of the Alzheimer's Type: An Important Risk Factor for Serious Falls
338 Citations1987Julie Morris, Eugene H. Rubin +2 more
Falls in SDAT participants were associated with an increased rate of institutionalization and males with SDAT who reported falls, had higher mean blood pressures and were more likely to be medicated than males withSDAT who did not fall.
The Journals of Gerontology Series BExercise and Depressive Symptoms: A Comparison of Aerobic and Resistance Exercise Effects on Emotional and Physical Function in Older Persons With High and Low Depressive Symptomatology
336 Citations2002Brenda W.J.H. Penninx, W. Jack Rejeski +5 more
Aerobic and resistance exercise significantly reduced disability and pain and increased walking speed both, and to an equal extent, in persons with high depressive symptom atology and persons with low depressive symptomatology.
NeurologyTreatment of agitation in AD
330 Citations2000Linda Teri, Rebecca G. Logsdon +15 more
Comparable modest reductions in agitation occurred in patients receiving haloperidol, trazodone, BMT, and placebo in the treatment of agitation in AD outpatients.
The Journals of Gerontology Series AA Randomized Outcome Evaluation of Group Exercise Programs in Long-Term Care Institutions
215 Citations1999D.-A. Lazowski, Nancy A. Ecclestone +7 more
Institutionalized seniors, even those who are physically frail, incontinent and/or have mild dementia, can respond positively to a challenging exercise program, and the FFLTC program demonstrated clear benefits over typical, seated ROM exercises.
Journal of the American Geriatrics SocietyA Walking Program for Nursing Home Residents: Effects on Walk Endurance, Physical Activity, Mobility, and Quality of Life
176 Citations1996Priscilla G. MacRae, Leslie A. Asplund +4 more
The effects of a 12‐week walking program on walk endurance capacity, physical activity level, mobility, and quality of life in ambulatory nursing home residents who had been identified as having low physical activity levels and low walk endurance capacities are studied.
The Journals of Gerontology Series ANursing Rehabilitation and Exercise Strategies in the Nursing Home
146 Citations1999J.N. Morris, M. A. Fiatarone +7 more
With both interventions, facilities were able to implement a broad-based intervention that resulted in a significant reduction in ADL decline rates, helping residents to maintain their involvement in a broad spectrum of ADL activities.
Archives of Physical Medicine and RehabilitationDoes functional reach improve with rehabilitation?
124 Citations1993Debra K. Weiner, Dennis Bongiorni +3 more
Functional reach is a precise, reliable, clinically accessible, age-sensitive measure of balance that approximates center of pressure excursion and validly estimates physical frailty and is suitable for use in prospective clinical trials.
Archives of Physical Medicine and RehabilitationExercise training in the debilitated aged: Strength and functional outcomes
116 Citations2000John R. Meuleman, William F. Brechue +2 more
This group of debilitated elderly patients effectively performed resistance training and increased their strength, with the most impaired gaining the most function.
Journal of Consulting and Clinical PsychologyAlzheimer's disease and depression.
111 Citations1992Linda Teri, Amy K. Wagner
There is accumulating evidence to suggest that depression affects a large number of patients with AD and can have profound effects on both the long-term functioning of these patients and the well-being of their caregivers.
Journal of the American Geriatrics SocietyDepression in Alzheimer's Disease Patients: Caregivers as Surrogate Reporters
107 Citations1995Rebecca G. Logsdon, Linda Teri
To evaluate the use of caregivers as surrogate reporters of depressive symptoms in Alzheimer's disease patients on five depression measures, a large number of patients with a history of depression were referred to a support group.
Journal of the American Geriatrics SocietyThe Seattle FICSIT/Movelt Study: The Effect of Exercise on Gait and Balance in Older Adults
104 Citations1993David M. Buchner, M. Elaine Cress +4 more
The Seattle FICSIT/Movelt study is a population‐based, randomized, controlled trial comparing the effects of three 6‐month exercise interventions (endurance training, strength training, or combined endurance and strength training), and three 3‐month endurance training interventions (stationary cycle, walking, or aerobic movement).
PubMedExercise and activity level in Alzheimer's disease: a potential treatment focus.
102 Citations1998Linda Teri, Susan M. McCurry +6 more
Findings indicate that the integration of exercise training into the care of persons with AD is both needed and feasible and that the efficacy of this approach for reducing additional physical disability in these individuals is currently underway.
Journal of the American Geriatrics SocietyEpidemiology of Injury in People with Alzheimer's Disease
85 Citations1995Denise M. Oleske, R. J. Wilson +3 more
This study characterizes all injuries incurred in a large sample of community‐dwelling persons with a specific form of dementia, Alzheimer's disease, to suggest that the risk of injury is elevated among persons with dementia.
Medical Clinics of North AmericaNonpharmacologic treatment of behavioral disturbance in dementia
80 Citations2002Linda Teri, Rebecca G. Logsdon +1 more
The article discusses current trends in clinical care along with specific strategies for treating and preventing some of the most common and debilitating behavioral problems of dementia patients: depression, agitation/aggression, wandering, and sleep disturbance.
The GerontologistElder Rehab: A Student-Supervised Exercise Program for Alzheimer's Patients
78 Citations1999Sharon M. Arkin, Nancy Morrow‐Howell
The University of Arizona Elder Rehab program offers independent study credit to students who serve as rehab partners and fitness supervisors to noninstitutionalized persons with dementia and may also be suitable for frail and depressed elderly persons without dementia.
International PsychogeriatricsWeight Loss in Alzheimer’s Disease: An International Review of the Literature
75 Citations1994Gisele Wolf‐Klein, Felix A. Silverstone
These findings suggest systemic, metabolic alterations in Alzheimer's disease that require further investigation as to their nature and as to the appropriate recognition and management to retard the deteriorating effects of chronic weight loss and malnutrition.
Journal of the American Geriatrics SocietyResponsiveness of Health Status Measures to Change among Older Adults
63 Citations1993Edward H. Wagner, Andrea Z. LaCroix +2 more
The ability of commonly used self‐reported health status measures to detect important changes in health (responsiveness) in older adults is examined.
The GerontologistThe Feasibility of Conducting Strength and Flexibility Programs for Elderly Nursing Home Residents With Dementia
57 Citations1995Nancy Wilson, Patricia A. Brill +3 more
It is concluded that this strength training program is feasible to conduct for elderly persons with dementia.
NeurologyAppendicular skeletal muscle mass, physical activity, and cognitive status in patients with Alzheimer's disease
49 Citations1998Roman Dvořák, Éric T. Poehlman
Higher levels of physical activity and energy intake are associated with higher appendicular skeletal muscle mass in AD patients and Nutritional and physical activity interventions may represent practical and inexpensive strategies in their therapeutic management.
American Journal of Public HealthTracking progress toward national health objectives in the elderly: what do restricted activity days signify?
41 Citations1991D. Scholes, Andrea Z. LaCroix +3 more
It was predicted that restricted activity days was more correlated with physical disability measures than with other health status measures and distributional properties and rates of missing data were shortcomings.
Medical CareCharacterizing Patient Dysfunction in Alzheimer??s-Type Dementia
34 Citations1988Claudia Krenz, Eric B. Larson +2 more
Comparing family member SIP scores for ATD and nondemented patients revealed that ATD patients maintained high levels of psychosocial dysfunction at both initial evaluation and 1-year follow-up, and physical deterioration over time is suggested.
