Biological membrane structure as “seen” by X-ray and neutron diffraction techniques
The Journal of Membrane BiologyPublished 1 February 1985
J. Kent Blasie, Leo G. Herbette, James M. Pachence
Citations20
SJR quartileQ2
SJR score0.70
SNIP0.60
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TL;DR
Time-averaged and time-resolved structural information may provide considerable insight into structure-function relationships in biological membranes and, especially when combined with structural information on the membrane proteins involved at atomic resolution, may provide this insight at the atomic level.
Abstract
The elastic X-ray/neutron diffraction techniques described in this review are currently capable of providing substantial information concerning the time-averaged structures and intermolecular ordering of molecular components within a dynamic membrane structure. In addition, the time resolution of the elastic X-ray diffraction technique, afforded by intense synchrotron and laser plasma X-ray sources, now permits this structural information to be obtained over a range of time scales from nanoseconds to milliseconds and upwards following an excitation of the membrane system. This time-averaged and time-resolved structural information may provide considerable insight into structure-function relationships in biological membranes and, especially when combined with structural information on the membrane proteins involved at atomic resolution, may provide this insight at the atomic level.
Keywords
Biochemistry, Genetics and Molecular Biology
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