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Association of Promoter Variants in the α7 Nicotinic Acetylcholine Receptor Subunit Gene With an Inhibitory Deficit Found in Schizophrenia

Archives of General PsychiatryPublished 1 December 2002
Sherry Leonard, Judith Gault, Jan Hopkins, Judith Logel, Ruby Vianzon, Margaret N. Short
Citations440

TL;DR

Although linkage disequilibrium with other genetic alterations cannot be excluded, the CHRNA7 core promoter variants, found in this study, may contribute to a common pathophysiologic feature of schizophrenia.

Abstract

Although linkage disequilibrium with other genetic alterations cannot be excluded, the CHRNA7 core promoter variants, found in this study, may contribute to a common pathophysiologic feature of schizophrenia.

Keywords

Biochemistry, Genetics and Molecular Biology