AGA technical review on irritable bowel syndrome
GastroenterologyPublished 26 November 2002Open access
Douglas A. Drossman, Michael Camilleri, Emeran A. Mayer, William E. Whitehead
Citations1,406
SJR quartileQ1
SJR score7.20
SNIP5.04
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TL;DR
Psychosocial factors, although not part of IBS per se, have an important role in modulating the illness experience and its clinical outcome.
Abstract
The irritable bowel syndrome (IBS) is part of the larger group of functional gastrointestinal (GI) disorders that, despite differences in location and symptom patterns, share common features with regard to their motor and sensory physiology, central nervous system (CNS) relationships, and the approach to patient care.1Drossman DA Corazziari E Talley NJ Thompson WG Whitehead WE. Rome II., The functional gastrointestinal disorders. Diagnosis, pathophysiology and treatment: a multinational consensus.2nd ed. Degnon Associates, McLean, VA2000Google Scholar IBS is a functional bowel disorder characterized by symptoms of abdominal pain or discomfort that is associated with disturbed defecation.2Thompson WG Longstreth GF Drossman DA Heaton KW Irvine EJ Mueller-Lissner SA. Functional bowel disorders and functional abdominal pain.Gut. 1999; 45: II43-II46Crossref PubMed Google Scholar This disorder is highly prevalent and can be associated with significant emotional distress, impaired health-related quality of life (HRQL), disability, and high health care costs. Psychosocial factors, although not part of IBS per se, have an important role in modulating the illness experience and its clinical outcome.3Thompson WG Longstreth GF Drossman DA Heaton KW Irvine EJ Mueller-Lissner SA.C. Functional bowel disorders and D. Functional abdominal pain.in: 2nd ed. Rome II: functional gastrointestinal disorders: diagnosis, pathophysiology, and treatment. Degnon Associates, Inc, McLean, VA2000: 351-432Google ScholarGASTROENTEROLOGY 2002;123:2108-2131
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248 Citations2001Francis Creed, Joy Ratcliffe +7 more
If impairment of health-related quality of life and increased health care and other costs are largely attributable to the psychological disturbance that often accompanies IBS, psychological treatment may improve these outcomes even if bowel symptoms change little.
GutPsychological significance of the irritable colon syndrome
248 Citations1971Ian Hislop
The symptom complex is considered to be a concomitant of an affective disorder, and the psychological factors associated with the genesis of the illness are discussed.
Digestive Diseases and SciencesHeightened visceral sensation in functional gastrointestinal disease is not site-specific
243 Citations1995Ken Trimble, Ridzuan Farouk +3 more
The findings indicate that alterations in visceral sensitivity in functional gastrointestinal disease affect sites in the gut other than the putative organ of symptom origin, supporting the concept of generally enhanced visceral awareness in patients with functional bowel disorders.
PainSelective attentional bias for pain-related stimuli amongst pain fearful individuals
241 Citations2001Edmund Keogh, Deborah Ellery +2 more
The results indicate that one reason why those with a high fear of pain are particularly susceptible to negative pain experiences could be due to biased attentional processes.
GutDysmotility of the small intestine in irritable bowel syndrome.
241 Citations1988John Kellow, S. F. Phillips +2 more
Several stimuli were applied in an attempt to unmask intestinal dysmotility in patients with IBS, finding that patients with diarrhoea were more sensitive to stimuli than those with constipation.
GastroenterologyHealth status by gastrointestinal diagnosis and abuse history
237 Citations1996DA Drossman, Zhongrui Li +3 more
The type of diagnosis and abuse history independently contributed to the health status of this population of patients and medical symptoms alone may not be sufficient to understand patients' health status.
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