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Origin of Concatemeric T7DNA

Nature New BiologyPublished 1 October 1972
James D. Watson
Citations1,606

TL;DR

The observed concatemers of T7 DNA are consistent with replication schemes resulting in double-helical molecules with 3´ ended tails and can then join to form dimers which on further replication similarly form larger concatemer.

Abstract

The observed concatemers of T7 DNA are consistent with replication schemes resulting in double-helical molecules with 3´ ended tails. Right-ended and left-ended molecules can then join to form dimers which on further replication similarly form larger concatemers.

Keywords

Biochemistry, Genetics and Molecular BiologyEnvironmental Science