Computational Analysis of Biochemical Systems: A Practical Guide for Biochemists and Molecular Biologists
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Abstract
Preface Introduction 1. Graphical representation of biochemical systems 2. Models of biochemical systems 3. From maps to equations 4. Computer simulation 5. Parameter estimation 6. Analytical steady-state evaluation 7. Sensitivity analysis 8. Case study 1 - Anaerobic fermentation pathway in Saccharomyces cerevisiae 9. Case study 2 - diagnosis and refinement of a model of the tricarboxylic acid cycle in Dictyostelium discoideum 10. Case study 3 - A sequence of models describing purine metabolism 11. Case study 4 - Algebraic analysis of the initial steps of the Glycolytic-Glycogenolytic pathway in perfused rat liver 12. Epilogue-Canonical modeling beyond biochemistry Appendix Hints and solutions References Author index Subject index.