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Defining the nature of the cerebral abnormalities in the premature infant: a qualitative magnetic resonance imaging study

The Journal of PediatricsPublished 1 August 2003
Terrie E. Inder, Scott J. Wells, N Mogridge, Carole A. Spencer, Joseph J. Volpe
Citations515
SJR quartileQ1
SJR score1.01
SNIP1.11

Abstract

This MRI study confirms a high incidence of cerebral white matter abnormality at term in an unselected population of premature infants, which is predominantly a result of noncystic injury in the extremely immature infant. We confirm that the major perinatal risk factors for white matter abnormality are related to perinatal infection, particularly maternal fever and infant sepsis, and hypotension with inotrope use. We have defined a distinct pattern of diffuse white and gray matter abnormality in the extremely immature infant.

Keywords

Medicine