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Global methylation in eutherian hybrids

NaturePublished 1 September 1999
Irmgard Roemer, Frank Grützner, Heinz Winking, Thomas Haaf, Annie Orth, Lulu Skidmore
Citations55
SJR quartileQ1
SJR score18.29
SNIP10.16

TL;DR

Evidence that global methylation patterns do not undergo dramatic changes in interspecific hybrids among three orders of placental mammals is presented, indicating that the mechanisms underlying genome evolution may be different in placental mammal and marsupials.

Abstract

O'Neill et al. propose that epigenetic pro-cesses help to drive karyotypic evolution in marsupials1. Here we present evidence that global methylation patterns do not undergo dramatic changes in interspecific hybrids among three orders of placental mammals, indicating that the mechanisms underlying genome evolution may be different in placental mammals and marsupials.

Keywords

Biochemistry, Genetics and Molecular Biology