Fortnightly Review: Diffuse lung disease: an approach to management
BMJPublished 16 July 1994Open access
R M du Bois
Citations31
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TL;DR
A recent survey of the management of fibrosing alveolitis in three regions in Britain revealed that few patients underwent investigations to confirm the diagnosis, and in clinical practice a clinician is consulted by a patient with a chest radiograph that shows widespread pulmonary shadows.
Keywords
Medicine
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514 Citations1980M Turner‐Warwick, Benjamin Burrows +1 more
A retrospective analysis of 220 cases fulfilling criteria for cryptogenic fibrosing alveolitis attending the Brompton Hospital between 1955 and 1973 has been carried out and patients have been followed for between four and 21 years, confirming the frequency of various clinical features.
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Analysis of retrospectively 100 consecutive patients with cryptogenic fibrosing alveolitis, who were treated with corticosteroids and followed for at least three years, showed a longer survival in younger patients and in patients with a shorter duration of symptoms before presentation, less radiographic abnormality, and less impairment of diffusing capacity.
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The diagnostic accuracy of death certification of cryptogenic fibrosing alveolitis is high, but the number of deaths recorded as being due to the disease may underestimate thenumber of patients dying with the disease by up to half.
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102 Citations1992J S Lee, J G Im +3 more
Ground-glass attenuation at HRCT is a good predictor of response to treatment in fibrosing alveolitis, and improvement in diffusing capacity for carbon monoxide, forced vital capacity, and forced expiratory volume after steroid treatment is correlated with improvement in pulmonary function.
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93 Citations1991Néstor L. Müller
This article compares the clinical usefulness of high-resolution CT with that of other diagnostic techniques and concludes that chronic diffuse lung disease is inappropriate for every patient.
European Respiratory JournalClearance of inhaled 99mTc-DTPA predicts the clinical course of fibrosing alveolitis
90 Citations1993AU Wells, D.M. Hansell +4 more
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Direct spin-echo chemical-shift imaging can help correlate MR images with histology by providing information not available from conventional or out-of-phase images.
ThoraxThe role of high resolution computed tomography in the diagnosis of interstitial lung disease.
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Improvements in computed tomographic scanner technology, notably in terms of spatial resolution and shorter scan times, have led to renewed interest in the application of computed tomography to show the fine morphological detail of the lung.
European Respiratory JournalThe management of cryptogenic fibrosing alveolitis in three regions of the United Kingdom
70 Citations1993I D Johnston, SA Gomm +4 more
There were wide variations of practice in the management of cryptogenic fibrosing alveolitis in the United Kingdom in the late 1980s, which is likely to reflect a paucity of information on the optimum management of this uncommon condition.
ThoraxOpen lung biopsy in patients with diffuse pulmonary shadowing.
35 Citations1985G Venn, Peter Kay +2 more
Open lung biopsy can be performed with minimal morbidity and a high diagnostic yield, and the approach used in this series provides a safe and reliable operation with good cosmetic results.
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10 Citations1992Raymond L. Tanner
Recommendations include levels of manual and automatic applied force, stability, reproducibility, and dependence on angulation and breast size and evaluation of operation of release mechanisms, as well as suggested tolerance limits.