A general method for the isolation of labelled peptides from affinity-labelled proteins
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TL;DR
The method makes use of the affinity of the native protein to the ligand that was used for labelling of the same protein to isolated the labelled peptide in one step in a very rapid procedure.
Abstract
A general method for specific isolation of ligand-bound peptides from affinity-labelled proteins is described. The method makes use of the affinity of the native protein to the ligand that was used for labelling of the same protein. Thus the labelled peptide can be isolated in one step in a very rapid procedure. The method was applied successfully to peptides from an antibody and from ribonuclease.