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Three-component process for the synthesis of 2-amino-2-chromenes in aqueous media

TetrahedronPublished 1 February 2001
Roberto Ballini, Giovanna Bosica, Maria Lina Conforti, Raimondo Maggi, Alessandro Mazzacani, Paolo Righi
Citations170
SJR quartileQ3
SJR score0.43
SNIP0.60

Abstract

The reaction of an aldehyde, malononitrile and a phenol in water at reflux in the presence of cetyltrimethylammonium chloride (CTACl) as catalyst affords a one-pot synthesis of 2-amino-2-chromenes. © 2001 Elsevier Science Ltd.

Keywords

ChemistryMedicine