Increasing Coverage in Mass Drug Administration for Lymphatic Filariasis Elimination in an Urban Setting: a Study of Malindi Town, Kenya
PLoS ONEPublished 14 January 2014Open access
Doris W. Njomo, Dunstan A. Mukoko, Nipher K. Nyamongo, Mary Joan Karanja
Citations56
SJR quartileQ1
SJR score0.80
SNIP1.07
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TL;DR
Improved treatment coverage in experimental sub-locations and spillover effects may have contributed to increased coverage in the control site and should be applied in urban areas.
Abstract
The identified strategies contributed to increased treatment coverage in experimental sites and should be applied in urban areas. Due to closeness of sites, spillover effects may have contributed to increased coverage in the control site.
Keywords
Immunology and MicrobiologyMedicine
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ParasitologyRe-assessing the global prevalence and distribution of lymphatic filariasis
531 Citations1996E. Michael, D. A. P. Bundy +1 more
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Filaria JournalSocial mobilisation, drug coverage and compliance and adverse reactions in a Mass Drug Administration (MDA) Programme for the Elimination of Lymphatic Filariasis in Sri Lanka
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PubMedCombination ivermectin plus diethylcarbamazine, a new effective tool for control of lymphatic filariasis.
43 Citations1995J.P. Moulia-Pelat, Philippe Glaziou +4 more
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