The Catalytic Asymmetric Mannich-Type Reactions in Aqueous Media
Journal of the American Chemical SocietyPublished 30 April 2002
Shū Kobayashi, Tomoaki Hamada, Kei Manabe
Citations217
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SJR score5.55
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TL;DR
The catalytic, diastereo- and enantioselective Mannich-type reaction of a hydrazono ester with silyl enol ethers in aqueous media has been successfully achieved with ZnF(2), a chiral diamine ligand, and trifluoromethanesulfonic acid.
Abstract
The catalytic, diastereo- and enantioselective Mannich-type reaction of a hydrazono ester with silyl enol ethers in aqueous media has been successfully achieved with ZnF(2), a chiral diamine ligand, and trifluoromethanesulfonic acid.
Keywords
ChemistryBiochemistry, Genetics and Molecular Biology
Critical Stability Constants
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