Positive regulation of the Escherichia coli glycine cleavage enzyme system
Journal of BacteriologyPublished 1 February 1993Open access
Rebecca L. Wilson, Paula S. Steiert, George V. Stauffer
Citations45
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TL;DR
Results suggest that gcvA encodes a positive-acting regulatory protein that acts in trans to increase expression of gcv.
Abstract
A new mutation in Escherichia coli, designated gcvA1, that results in noninducible expression of both gcv and a gcvT-lacZ gene fusion was isolated. A plasmid carrying the wild-type gcvA gene complemented the mutation and restored glycine-inducible gcv and gcvT-lacZ gene expression. These results suggest that gcvA encodes a positive-acting regulatory protein that acts in trans to increase expression of gcv.
Keywords
Materials ScienceBiochemistry, Genetics and Molecular Biology
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