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Circadian Rhythm of Serotonin in the Pineal Body of Immunosympathectomized Immature Rats

SciencePublished 25 April 1969
Conceição R.S. Machado, Laurence E. Wragg, Ângelo B. M. Machado
Citations36
SJR quartileQ1
SJR score10.42
SNIP6.62

TL;DR

In the pineal body of the immature rat the circadian rhythm of serotonin persists when sympathetic innervation is abolished by the administration of nerve growth factor antiserum, and is fundamentally different from that in the adult.

Abstract

In the pineal body of the immature rat the circadian rhythm of serotonin persists when sympathetic innervation is abolished by the administration of nerve growth factor antiserum. This rhythm is regulated by a mechanism that does not involve the sympathetic innervation and is, therefore, fundamentally different from that in the adult.

Keywords

Neuroscience