Pseudomonas acquisition in young patients with cystic fibrosis: pathophysiology, diagnosis, and management
Current Opinion in Pulmonary MedicinePublished 10 October 2003
Margaret Rosenfeld, Bonnie W. Ramsey, Ronald L. Gibson
Citations120
SJR quartileQ2
SJR score0.81
SNIP0.72
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TL;DR
There is a critical need for further investigation of the clinical outcomes associated with early intervention, the long-term safety profile, and the optimal drug regimen for early Pa infection in CF patients.
Abstract
Anti-pseudomonal therapy for early infection results in transient Pa eradication, but re-infection with Pa appears inevitable despite early aggressive treatment. There are no controlled trials demonstrating clinical benefit in young children. There is a critical need for further investigation of the clinical outcomes associated with early intervention, the long-term safety profile, and the optimal drug regimen.
Keywords
Medicine
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