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Anti‐Fy5, an Antibody Disclosing a Probable Association between the Rhesus and Duffy Blood Group Genes

Vox SanguinisPublished 1 March 1973
Katharine I. Colledge, Marisa Pezzulic, W. L. Marsh
Citations49
SJR quartileQ2
SJR score0.56
SNIP0.90

TL;DR

The data suggest that the Fy5 determinant is formed by interaction of Rhesus and Duffy gene products.

Abstract

Abstract. A new antibody, anti‐Fy5, has been found in the serum of a Negro Fy(a–b–) person. It reacts with Fy(a+) or Fy(b+) red cells of common Rh type, but not with Fy(a–b–) cells from Negroes, or with Rh null cells. An example of Caucasian Fy(a–b–) red cells was Fy5 positive. U‐negative or LW‐negative red cells give the reaction expected of their Duffy type. The data suggest that the Fy5 determinant is formed by interaction of Rhesus and Duffy gene products.

Keywords

Immunology and MicrobiologyMedicine