Acute bilateral blindness caused by accidental methanol intoxication during fire "eating"
British Journal of OphthalmologyPublished 1 September 2002Open access
Claus Cursiefen
Citations20
SJR quartileQ1
SJR score1.81
SNIP1.83
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
Keywords
Medicine
New England Journal of MedicineFomepizole for the Treatment of Methanol Poisoning
400 Citations2001Jeffrey Brent, Kenneth E. McMartin +3 more
Fomepizole appears to be safe and effective in the treatment of methanol poisoning and nine patients survived and two patients who died had anoxic brain injury that was present at the time of enrollment.
RetinaINTRAVITREAL TRIAMCINOLONE ACETONIDE IN EXUDATIVE AGE-RELATED MACULAR DEGENERATION
381 Citations2000Ronald P. Danis, Thomas A. Ciulla +1 more
Intravitreal triamcinolone acetonide may provide short‐term improvement in visual acuity and fundus findings in exudative macular degeneration and should be followed by multicenter, masked, placebocontrolled trials with long‐term follow-up.
Australian and New Zealand Journal of OphthalmologyExudative macular degeneration and intravitreal triamcinolone: 18 month follow up
326 Citations1998Jagannadh K Challa, Mark C. Gillies +4 more
The results of the present study suggest that a single intravitreal injection of 4 mg triamcinolone is reasonably well tolerated by the human eye, and the rate of development of severe visual loss was less than reported for historical controls.
PubMedTreatment of intraocular proliferations with intravitreal steroids.
275 Citations1979Robert Machemer, Gentaro Sugita +1 more
Autotransplantation of 250,000 tissue cultured fibroblasts from rabbit rump skin into the vitreous cavity results in intravitreal strand formation and traction retinal detachment and inhibits fibroblast growth.
Journal of neurosurgeryTime course of blood velocity changes related to vasospasm in the circle of Willis measured by transcranial Doppler ultrasound
270 Citations1987A. Härders, Joachim M. Gilsbach
American Journal of OphthalmologyIntravitreal injection of crystalline cortisone as adjunctive treatment of proliferative diabetic retinopathy
242 Citations2001Jost B Jonas, Jochen Hayler +2 more
Archives of OphthalmologyCentral Serous Chorioretinopathy in Endogenous Hypercortisolism
240 Citations1993Evrydiki A. Bouzas
Since central serous chorioretinopathy has been associated with other hypercortisolemic states, it is suggested that glucocorticoids may play a role in the development of this disease.
American Journal of OphthalmologyThe Clearance of Intravitreal Triamcinolone Acetonide
209 Citations1982Reinhardt H. Schindler, David Chandler +2 more
It is suggested that more frequent injections of triamcinolone acetonide would be necessary in eyes that underwent vitrectomy, compared with normal eyes, and direct observation is an accurate method of assessing the absorption of the corticosteroid.
OphthalmologyCentral Serous Chorioretinopathy Associated with Inhaled or Intranasal Corticosteroids
162 Citations1997Robert Haimovici, Evangelos S. Gragoudas +3 more
Findings suggest that, in patients who are susceptible, the periocular or systemic absorption of inhaled corticosteroids may be sufficient to produce central serous chorioretinopathy in humans, supporting previous hypotheses regarding the pathogenesis of the disorder.
British Journal of OphthalmologyCentral serous chorioretinopathy complicating systemic corticosteroid treatment.
162 Citations1984Masato Wakakura, Satoshi Ishikawa
Central serous chorioretinopathy developed in 2 cases of retrobulbar neuritis during systemic treatment with corticosteroids and it is suggested that high dosage corticaosteroids may damage the posterior blood-ocular barrier.
NeurologyMethanol optic neuropathy
153 Citations1982James Sharpe, Michael Hostovsky +2 more
The histopathologic effects of methanol on the optic nerve were studied in four patients and Retrolaminar demyelinating optic neuropathy is an early morphologic correlate of visual loss in meethanol intoxication.
PubMedIntravitreal triamcinolone acetonide in exudative age-related macular degeneration.
152 Citations2000R P Danis, Thomas A. Ciulla +2 more
PubMedAntimetabolite-induced apoptosis in Tenon's capsule fibroblasts.
151 Citations1998Jonathan G. Crowston, Arne N. Akbar +4 more
Mitomycin-C and high-dose 5-fluorouracil induce apoptosis in cultured Tenon's fibroblasts and is inhibited by fetal calf serum, indicating that exogenous factors influence the susceptibility of a fibroblast population to apoptosis.
OphthalmologicaPosterior Ischemic Optic Neuropathy
136 Citations2010Sohan Singh Hayreh
3 patients with posterior ischemic optic neuropathy with visual acuity varying from normal to no light perception, optic nerve-related visual field defects, and no fundus abnormality are presented.
Lara D. VeekenINTRAVENOUS IMMUNOGLOBULIN AS SOLE THERAPY FOR SYSTEMIC VASCULITIS
131 Citations1995David Jayne, C M Lockwood
High-dose, pooled, i.v. immunoglobulin (IVIg) is a potential, alternative treatment for Wegener's granulomatosis and microscopic polyangiitis which has shown promise in the treatment of refractory disease when administered with continuing immunosuppression.
British Journal of OphthalmologyOcular changes in limited forms of Wegener's granulomatosis.
129 Citations1981D J Spalton, E. M. Graham +2 more
Eight patients who had limited forms of Wegener's granulomatosis are described, with details of their pathology.
OphthalmologyIntraocular Pressure Elevation Associated with Inhalation and Nasal Corticosteroids
122 Citations1995Ira Opatowsky, Robert Feldman +2 more
Cognitive hypertensive response to corticosteroids by nasal spray or inhalation may cause ocular hypertension in susceptible patients and the authors recommend surveillance of IOP in patients using these medications.
OphthalmologyLong-term Visual Outcome in Terson Syndrome
120 Citations1991Paul N. Schultz, Warren M. Sobol +1 more
Visual recovery was more rapid in eyes undergoing vit rectomy despite the fact that vitrectomy was reserved for eyes with more dense vitreous hemorrhage, and there was no difference in final visual outcome between those patients undergoing Vitrectomy and those managed conservatively.
OphthalmologyAcute Obstruction of the Retinal and Choroidal Circulations
120 Citations1986Gary C. Brown, Larry E. Magargal +1 more
The cases of eight patients (10 eyes) with the equivalent of an acute ophthalmic artery obstruction (simultaneous impairment of both the retinal and choroidal circulations) are described, carrying a grim visual prognosis, as all ten eyes initially had no perception of light.
Mayo Clinic ProceedingsWegener's Granulomatosis Associated With Vasculitis of the Temporal Artery: Report of Five Cases
104 Citations1993Hiroshi Nishino, Richard A. DeRemee +2 more
Between January 1973 and October 1991 at the Mayo Clinic, 5 of 345 patients with Wegener's granulomatosis initially had features suggestive of giant cell arteritis and subsequently were found to have biopsy-proven vasculitis of the temporal artery.
PubMedDevelopment and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity.
95 Citations2000Janis T. Eells, Michele M. Henry +3 more
The functional and morphologic findings in methanol-intoxicated rats are consistent with the hypothesis that formate acts as a mitochondrial toxin in the retina and optic nerve, and the establishment and characterization of this nonprimate animal model of meethanol intoxication will facilitate research into the mechanistic aspects of methnol toxicity and the development and testing of treatments for human methanl poisoning.
Australian and New Zealand Journal of OphthalmologyAcute ocular methanol toxicity: Clinical and electrophysiological features
81 Citations1997Malcolm McKellar, Rudy R. Hidajat +1 more
The data presented suggest that methanol affects the photoreceptors, Muller cells and the retrolaminar portion of the optic nerve and can cause characteristic ocular damage, together with widespread electrophysiological dysfunction.
American Journal Of PathologyComparative Analysis of Different Methodological Approaches to the in Vitro Study of Drug-Induced Apoptosis
81 Citations1999Vladimir D. Kravtsov, Thomas O. Daniel +1 more
Both a maximum apoptotic response and the time at which it was achieved are the obligatory requirements for determining the apoptosis-inducing potency of an agent and for comparing results of studies performed in different laboratories.
PubMedDifferential recovery of retinal function after mitochondrial inhibition by methanol intoxication.
75 Citations2001M T Seme, Phyllis Summerfelt +3 more
Findings support the hypothesis that formate inhibits retinal mitochondrial function and increases oxidative stress and provide evidence for a differential sensitivity of photoreceptors to the cytotoxic actions of formic acid.
NeuroradiologyNecrosis and haemorrhage of the putamen in methanol poisoning shown on MRI
74 Citations1998Khaldoun Kuteifan, Hélène Oesterle +3 more
A 50-year-old woman with accidental methanol intoxication who was in a vegetative state was described, and MRI showed haemorrhagic necrosis of the putamina and oedema in the deep white matter.
International OphthalmologyAcute blindness and putaminal necrosis in methanol intoxication
74 Citations1998Feyza Önder, Sami İlker +3 more
Methanol intoxication is detrimental to health, possibly resulting in blindness and occasionally death, and the ophthalmologist should be alert to the diagnosis of methanol intoxication in which visual loss may be the only symptom.
Current Opinion in OphthalmologyOcular manifestations of giant cell arteritis
68 Citations1998José Luis Tovilla-Canales
This work presents new insights into the epidemiology and pathophysiology of giant cell arteritis that may improve early diagnosis and treatment of the disease.
AIDS Research and Human RetrovirusesComparison of Seven Quantitative Assays to Assess Lymphocyte Cell Death during HIV Infection: Measurement of Induced Apoptosis in Anti-Fas-Treated Jurkat Cells and Spontaneous Apoptosis in Peripheral Blood Mononuclear Cells from Children Infected with HIV
46 Citations1998Thomas W. McCloskey, Surendra Chavan +2 more
The results showed that the trypan blue test was unacceptable for quantification of apoptosis during HIV infection, whereas TUNEL, of all the methods tested, showed excellent overall correlation in both cell systems, was highly specific, and matched microscopic observation of the cells.
Journal of Toxicology Clinical ToxicologyMethanol-Related Deaths in Ontario
40 Citations1999Julia J. Liu, Mohamud Daya +1 more
Over half of the methanol-related deaths in Ontario are accidental and potentially preventable, and possible preventative strategies include mandatory product relabeling to eliminate the word alcohol, enhanced public education, and the addition of aversive agents to methnol-containing commercial products.
OphthalmologicaRetinal Pigment Epithelial Changes Associated with Systemic Corticosteroid Treatment: Report of Cases and Review of the Literature
33 Citations1998Christoph W. Spraul, Gabriele E. Lang +1 more
These 4 patients provide further evidence that systemic treatment with corticosteroids may cause central serous chorioretinopathy or diffuse retinal pigment epitheliopathy, and ophthalmologic examination is recommended on a regular basis for patients treated with systemic cortICosteroids.
EyeLeft atrial myxoma causing ophthalmic artery occlusion
31 Citations1997Paul E. Rafuse, David A. Nicolle +2 more
A 45-year-old Caucasian woman presented with sudden onset right-sided hemiparesis, aphasia and a painful left eye, and examination revealed a bone-white fundus with no perfusion of either the retinal or choroidal circulations.
PubMedBilateral isolated retrobulbar optic neuropathy in limited Wegener's granulomatosis.
27 Citations1993Belden Cj, Hamed Lm +1 more
A patient who presented with bilateral, isolated, consecutive, posterior optic neuropathy with light perception and no light perception vision may pose a diagnostic quandary of Wegener's granulomatosis.
Journal of Toxicology Clinical ToxicologyFomepizole (4-Methylpyrazole) in Fatal Methanol Poisoning with Early CT Scan Cerebral Lesions
26 Citations1999Christophe Girault, Fabienne Tamion +5 more
The fomepizole treatment protocol was simple to use and appeared effective in eliminating methanol in combination with hemodialysis and the early onset of cerebral lesions demonstrated by computed tomography (CT) scan.
American Journal of OphthalmologyMethanol Optic Neuropathy. A Histopathological Study.
17 Citations1983James Sharpe, M. Hostovsky +2 more