Organocatalytic asymmetric allylic amination of Morita–Baylis–Hillman carbonates of isatins
Beilstein Journal of Organic ChemistryPublished 6 August 2012Open access
Hang Zhang, Shanjun Zhang, Qingqing Zhou, Lin Dong, Ying‐Chun Chen
Citations31
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SJR score0.48
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Abstract
The investigation of a Lewis base catalyzed asymmetric allylic amination of Morita-Baylis-Hillman carbonates derived from isatins afforded an electrophilic pathway to access multifunctional oxindoles bearing a C3-quaternary stereocenter, provided with good to excellent enantioselectivity (up to 94% ee) and in high yields (up to 97%).
Keywords
Chemistry
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