Repair of X-ray damage in aging WI-38 cells
Mutation Research/Fundamental and Molecular Mechanisms of MutagenesisPublished 1 April 1974
Judith M. Clarkson, Robert B. Painter
Citations61
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TL;DR
It is concluded that reduced efficiency in one or both of them is not responsible for in vitro aging of human cells in young ad old X-irradiated WI-38 cells.
Abstract
Rate of strand rejoining and the ability to perform repair replication were determined in young ad old X-irradiated WI-38 cells. No differences in either process were apparent and we conclude that reduced efficiency in one or both of them is not responsible for in vitro aging of human cells.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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