Effects of Lowering Elevated LDL Cholesterol on the Cardiovascular Risk of Lipoprotein(a)
JAMAPublished 13 December 1995
Vincent Maher
Citations291
SJR quartileQ1
SJR score5.35
SNIP10.71
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TL;DR
In men with CAD and elevated LDL-C, Lp(a) levels were dominant correlates of baseline disease severity, its progression, and event rate over 2.5 years.
Abstract
In men with CAD and elevated LDL-C, Lp(a) levels were dominant correlates of baseline disease severity, its progression, and event rate over 2.5 years. However, with substantial LDL-C reductions, persistent elevations of Lp(a) were no longer atherogenic or clinically threatening. This provides a possible direction for treatment in such patients with elevated Lp(a) and LDL-C.
Keywords
Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology
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